Cliffs notes (remember those?) for yesterday's article about the mRNAs and IgG4

The science can be confusing, but it's vital. A reader did a great job explaining it in a few sentences. I've cut and pasted his comment below. (Plagiarism? I prefer to think of it as homage!)

I do my best to make the science around the mRNAs manageable, but as you know, I don’t always succeed, especially when the immunology gets complex. (Epidemiology is way easier to explain; it’s basically just statistical connections.)

But understanding the issue of the mRNAs and IgG4 is crucial. No one predicted the mRNAs would have this effect, and other Covid vaccines do not. It is probably the biggest long-term “tail risk” that vaccinated people now face.

Anyway, if you found yesterday’s piece tough sledding, this comment from Dr. Kevin McQuaid may help. (And yes, someone by that name is a pathologist AND an Unreported Truths subscriber.) He offers a great succinct summary of why IgG4 levels are rising and what that that rise may mean - though, again, as long as Omicron remains mild, the risks are mostly theoretical.

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(Be like Dr. McQuaid! Subscribe! Then you too can comment on articles - and with any luck your brilliant words will go out to hundreds of thousands of Unreported Truths subscribers. I know, I know, dreams do come true!)

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From Dr. Kevin McQuaid:

Although I am a pathologist and not an immunologist, everything in this article is perfectly logical from an immune system perspective. IgG4 is a subclass of gamma globulin [Note: gamma globulin is a medical term that essentially means antibody] that rises with repeated antigen exposure. In a sense it turns down the immune system to repeated antigen exposure. That is an adaptive mechanism for something like exposure to pollen, or tropomyosin, or legumes.

But it is maladaptive when that antigen (in this case spike protein) comes along with a pathogenic virus attached. Colbert’s immune system has habituated to the COVID spike so, along with the damage done by the vax to the interferon system, he can’t clear the virus. [Note: I mentioned Stephen Colbert’s new case of Covid in the article.] All of that is bad enough, but if the virus were to mutate into a more virulent strain he and all the others like him are going to be in serious trouble.

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In case you missed the piece, or want to read it again now that Dr. McQuaid has explained it: