Something wicked this way comes (and by something, I mean mRNA immune system dysregulation)

Why the paper reporting an explosion in IgG4 antibodies after the mRNA boosters is so unsettling - in a hopefully easy to understand Q+A

Hope you enjoyed the last week of 2022… and now back to business.

—

Time for a story in Q+A format. Why?

By now, you have probably heard about the Science Immunology paper showing that people who have received mRNA Covid vaccines produce more of an unusual antibody called IgG4 over time. A number of mRNA skeptics, including me, wrote about it last week.

Bu…